Impacts of active urea secretion into pars recta on urine concentration and urea excretion rate
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Impacts of active urea secretion into pars recta on urine concentration and urea excretion rate
It has been observed experimentally that early distal tubular urea flow exceeds urea delivery by the proximal convoluted tubule to the pars recta and loop of Henle. Moreover, the fractional excretion of urea in the urine may exceed values compatible with the reabsorption known to occur in the proximal convoluted tubule in the cortex. A likely explanation for these observations is that urea may ...
متن کاملThe Rate of Urea Excretion. Iii. the Effect of Changes in Blood Urea Concentration on the Rate of Urea Excretion. by T. Addis and C. K. Watanabe
On one side of the urea-secreting cells of the kidney there is blood and on the other side there is urine. The rate of urea excretion is the rate at which these cells transfer urea from blood to urine. Under these circumstances it seems probable that changes in the concentration of urea in the ,blood will have an effect on the rate of urea excretion. If the concentration of urea in the blood we...
متن کاملThe Rate of Urea Excretion. Vii. the Effect of Various Other Factors than Blood Urea Concentration on the Rate of Urea Excretion.* by T. Addis
tions a constant (1). If now these conditions are all complied with, but in addition some new factor is introduced, the effect on the rate of urea excretion can be measured by the deviation of the ratio from its constant value. Most of the experiments given in this paper were carried out on the two subjects, Add. and Dru., whose ratios under standard conditions are given in Paper V of this seri...
متن کاملThe Effect of Urine Volume on Urea Excretion.
In recent papers Bing (1) and Williams (2) have proposed formulae which these authors believe to be more accurate than the original "standard" and "maximum" clearance equations of M6ller, McIntosh, and Van Slyke (3, 4), in expressing the effects of urine volume flow on the urea clearance in human subjects. Both Bing and Williams base their formulae on the data of M6ller et al (3). The essential...
متن کاملThe Rate of Urea Excretion. Iv. the Effect of Changes in the Volume of Urine on the Rate of Urea Excretion
Since the concentration of urea in the blood influences the rate at which urea passes through the urea-secreting cells of the kidney, it seems likely that the concentration of urea in the urine in contact with the internal surfaces of these cells should also have an effect. A high concentration would tend to delay, and a low concentration to facilitate the discharge of urea from the cells, at l...
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ژورنال
عنوان ژورنال: Physiological Reports
سال: 2013
ISSN: 2051-817X
DOI: 10.1002/phy2.34